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    本书是《奈特图解医学全书》第2卷内分泌系统疾病（第2版）。《奈特图解医学全书》是世界著名医学绘图类品牌图书，涵盖了人体的九大系统，内容包括解剖、发育、生理、病理等基础学科知识及临床疾病诊治要点，全书绘图精美、叙述简明扼要，堪称医学与艺术、基础与临床的完美结合。影印版采用全彩色印刷，读者既可领略到“奈特”形象逼真的绘图，也可学习原汁原味的医学英语，是医学生、临床医生的优秀读物。

    维利姆·杨，William F.Young,Jr,MD,MSc,is Professorof Medicine at Mayo Clinic College ofMedicine,Mayo Clinic,Rochester,Minnesota,USA.He holds the Tyson Family Endocrinology ClinicalProfessorship in Honor of Vahab Fatourechi,MD.Hereceived his bachelor degree and his medical degreefrom Michigan State University and his master ofscience degree from the University of Minnesota.Dr.Young trained in internal medicine at William Beau-mont Hospital in Royal Oak,Michigan,and completeda fellowship in endocrinology and metabolism at MayoClinic in Rochester,Minnesota.He has been a memberof the staff at Mayo Clinic since 1984.Dr.Young isthe recipient of multiple education awards includingthe Mayo Fellows Association Teacher of the YearAward in Internal Medicine,the Mayo Clinic Endocri-nology Teacher of the Year Award,the Mayo Schoolof Continuing Medical Education Outstanding FacultyMember Award,and the H.Jack Baskin,MD,Endo-crine Teaching Award from the American Associationof Clinical Endocrinologists in recognition of hisprofound impact in teaching fellows in training.Professional honors include being a recipient of theDistinguished Mayo Clinician Award,the Distinctionin Clinical Endocrinology Award from the AmericanCollege of Endocrinology,and the DistinguishedPhysician Award from the Endocrine Society.Dr.Young's clinical research focuses on primary aldoste-ronism and pheochromocytoma.He has publishedmore than 200 articles on endocrine hypertension andadrenal and pituitary disorders.Dr.Young has pre-sented at more than 300 national and internationalmeetings and has been an invited visiting professor atmore than 100 medical institutions.

SECTION 1
  PITUITARY AND
  HYPOTHALAMUS
  1-1 Development of the Pituitary Cland
  1-2 Divisions of the Pituitary Cland and
  Relationship to the Hypothalamus
  1-3 Blood Supply of the Pituitary Cland
  1-4 Anatomy and Relationships of the
  Pituitary Gland
  1-5 Relationship of the Pituitary Cland to the
  Cavernous Sinus
  1-6 Relationships of the Sella Turcica
  1-7 Anterior Pituitary Hormones and Feedback
  Control
  1-8 Posterior Pituitary Gland
  1-9 Manifestations of Suprasellar Disease
  1-10 Craniopharyngioma
  1-11 Effects of Pituitary Tumors on the Visual
  Apparatus
  1-12 Nontumorous Lesions of the Pituitary
  Gland and Pituitary Stalk
  1-13 Pituitary Anterior Lobe Deficiency in
  Childhood and Adolescence in Boys
  1-14 Pituitary Anterior Lobe Deficiency in
  Adults
  1-15 Selective and Partial Hypopituitarism
  1-16 Severe Anterior Pituitary Deficiency or
  Panhypopituitarism
  1-17 Postpartum Pituitary Infarction (Sheehan
  Syndrome)
  1-18 Pituitary Apoplexy
  1-19 Pituitary Cigantism
  1-20 Acromegaly
  1-21 Prolactin-Secreting Pituitary Tumor
  1-22 Corticotropin-Secreting Pituitary
  Tumor
  1-23 Nelson Syndrome
  1-24 Clinically Nonfunctioning Pituitary
  Tumor
  1-25 Secretion and Action of Oxytocin
  1-26 Secretion and Action of Vasopressin
  1-27 Central Diabetes Insipidus
  1-28 Langerhans Cell Histiocytosis in
  Children
  1-29 Langerhans Cell Histiocytosis in
  Adults
  1-30 Tumors Metastatic to the Pituitary
  1-31 Surgical Approaches to the Pituitary
SECTION 2
  THYROID
  2-1 Anatomy of the Thyroid and Parathyroid
  Glands
  2-2 Anatomy of the Thyroid and Parathyroid
  Glands(cont'd)
  2-3 Development of the Thyroid and
  Parathyroid Clands
  2-4 Development of the Thyroid and
  Parathyroid Glands(cont'd)
  2-5 Congenital Anomalies of the Thyroid
  Gland
  2-6 Effects of Thyrotropin on the Thyroid
  Gland
  2-7 Physiology of Thyroid Hormones
  2-8 Graves Disease
  2-9 Graves Disease(cont'd)
  2-10 Graves Ophthalmopathy
  2-11 Thyroid Pathology in Craves Disease
  2-12 Clinical Manifestations of Toxic Adenoma
  and Toxic Multinodular Goiter
  2-13 Pathophysiology of Toxic Adenoma and
  Toxic Multinodular Coiter
  2-14 Clinical Manifestations of Hypothyroidism
  in Adults
  2-15 Clinical Manifestations of Hypothyroidism
  in Adults (cont'd)
  2-16 Clinical Manifestations of Hypothyroidism
  in Adults(cont'd)
  2-17 Congenital Hypothyroidism
  2-18 Euthyroid Goiter
  2-19 Gross Pathology of Coiter
  2-20 Etiology of Nontoxic Goiter
  2-21 Chronic Lymphocytic Thyroiditis and
  Fibrous Thyroiditis
  2-22 Subacute Thyroiditis
  2-23 Papillary Thyroid Carcinoma
  2-24 Follicular Thyroid Carcinoma
  2-25 Medullary Thyroid Carcinoma
  2-26 Hurthle Cell Thyroid Carcinoma
  2-27 Anaplastic Thyroid Carcinoma
  2-28 Tumors Metastatic to the Thyroid
SECTION 3
  ADRENAL
  3-1 Development of the Adrenal Clands
  3-2 Anatomy and Blood Supply of the Adrenal
  Glands
  3-3Anatomy and Blood Supply of the Adrenal
  Clands(cont'd)
  3-4 Innervation of the Adrenal Clands
  3-5 Histology of the Adrenal Clands
  3-6 Biosynthesis and Metabolism of Adrenal
  Cortical Hormones
  3-7 Biosynthesis and Metabolism of Adrenal
  Cortical Hormones(cont'd)
  3-8 The Biologic Actions of Cortisol
  3-9 Cushing Syndrome-Clinical Findings
  3-10 Tests Used in the Diagnosis of Cushing
  Syndrome
  3-11 Cushing Syndrome:Pathophysiology
  Cushing Syndrome Caused by Primary
  3-12 Pigmented Nodular Adrenocortical
  Disease
  Major Blocks in Abnormal
  3-13 Steroidogenesis
  3-14 Classic Congenital Adrenal
  Hyperplasia
  3-15 The Biologic Actions of Adrenal
  Androgens
  3-16 Adult Androgenital Syndromes
  3-17 The Biologic Actions of Aldosterone
  3-18 Primary Aldosteronism
  3-19 Adrenal Venous Sampling for Primary
  Aldosteronism
  3-20 Renin-Angiotensin-Aldosterone System
  and Renovascular Hypertension
  3-21 Acute Adrenal Failure-Adrenal
  Crisis
  3-22 Chronic Primary Adrenal Failure-
  Addison Disease
  3-23 Laboratory Findings and Treatment of
  Primary Adrenal Insufficiency
  3-24 Laboratory Findings and Treatment of
  Secondary Adrenal Insufficiency
  3-25Adrenal Medulla and Catecholamines
  3-26 Catecholamine SynthesisStorage
  SecretionMetabolismand
  Inactivation
  3-27 Pheochromocytoma and
  Paraganglioma
  3-28 Pheochromocytoma and
  Paraganglioma(cont'd)
  3-29 Tumors Metastatic to the Adrenal
  Clands
SECTION 4
  REPRODUCTION
  4-1 Differentiation of Conads
  4-2 Differentiation of Genital Ducts
  4-3Differentiation of External Cenitalia
  4-4Testosterone and Estrogen Synthesis
  4-5 Normal Puberty
  4-6 Normal Puberty(cont'd)
  4-7 Normal Puberty (cont'd)
  4-8 Normal Puberty(cont'd)
  4-9 Precocious Puberty
  4-10 Precocious Puberty(cont'd)
  4-11 Precocious Puberty(cont'd)
  4-12 Disorders of Sex Development
  4-13Disorders of Sex Development
  (cont'd)
  4-14 Disorders of Sex Development
  (cont'd)
  4-15 Disorders of Sex Development
  (cont'd)
  4-16 Errors in Chromosomal Sex
  4-17 Klinefelter Syndrome
  4-18 Turner Syndrome(Gonadal
  Dysgenesis)
  4-19 Turner Syndrome(Conadal Dysgenesis)
  (cont'd)
  4-20 Turner Syndrome(Conadal Dysgenesis)
  (cont'd)
  4-21 Hirsutism and Virilization
  4-22 Hirsutism and Virilization (cont'd)
  4-23 Influence of Gonadal Hormones on the
  Female Reproductive Cycle from Birth to
  Old Age
  4-24 Functional and Pathologic Causes of
  Uterine Bleeding
  4-25 Gynecomastia
  4-26 Galactorrhea
SECTION 5
  PANCREAS
  5-1 Pancreas Anatomy and Histology
  5-2 Exocrine Functions of the Pancreas
  5-3Normal Histology of Pancreatic
  Islets
  5-4 Insulin Secretion
  5-5 Actions of Insulin
  5-6 Clycolysis
  5-7 Tricarboxylic Acid Cycle
  5-8 Clycogen Metabolism
  5-9 Consequences of Insulin Deprivation
  5-10 Diabetic Ketoacidosis
  5-11 Type l Diabetes Mellitus
  5-12 Type 2 Diabetes Mellitus
  5-13Diabetic Retinopathy
  5-14 Complications of Proliferative Diabetic
  Retinopathy
  5-15 Diabetic Nephropathy
  5-16 Diabetic Neuropathy
  5-17 Atherosclerosis in Diabetes
  5-18 Vascular Insufficiency in Diabetes:The
  Diabetic Foot
  5-19 Diabetes Mellitus in Pregnancy
  5-20 Treatment of Type 2 Diabetes
  Mellitus
  5-21 Treatment of Type 1 Diabetes
  Mellitus
  5-22 Insulinoma
  5-23 Primary Pancreatic β-Cell Hyperplasia
SECTION 6
  BONE AND CALCIUM
  6-1 Histology of the Normal Parathyroid
  Clands
  6-2 Physiology of the Parathyroid Clands
  6-3 Bone Remodeling Unit
  6-4 Pathophysiology of Primary
  Hyperparathyroidism
  6-5 Pathology and Clinical Manifestations of
  Primary Hyperparathyroidism
  6-6 Tests for the Differential Diagnosis of the
  Causes of Hypercalcemia
  6-7 Renal Osteodystrophy
  6-8 Renal Osteodystrophy:Bony
  Manifestations
  6-9 Histology of the Parathyroid Clands in
  Hyperparathyroidism
  6-10 Pathophysiology of
  Hypoparathyroidism
  6-11 Clinical Manifestations of Acute
  Hypocalcemia
  6-12 Pathophysiology of
  Pseudohypoparathyroidism
  6-13 Clinical Manifestations of
  Pseudohypoparathyroidism Type la
  6-14 Pathogenesis of Osteoporosis
  6-15 Osteoporosis in Postmenopausal
  Women
  6-16 Osteoporosis in Men
  6-17 Clinical Manifestations of Osteoporotic
  Vertebral Compression Fractures
  6-18 Nutritional-Deficiency Rickets and
  Osteomalacia
  6-
  Pseudovitamin D-Deficiency Rickets and
  Osteomalacia
  6-20 Hypophosphatemic Rickets
  6-21 Clinical Manifestations of Rickets in
  Childhood
  6-22 Clinical Manifestations of Osteomalacia in
  Adults
  6-23 Paget Disease of the Bone
  6-24 Pathogenesis and Treatment of Paget
  Disease of the Bone
  6-25 Osteogenesis Imperfecta
  6-26 Osteogenesis Imperfecta(cont'd)
  6-27 Hypophosphatasia
SECTION 7
  LIPIDS AND NUTRITION
  7-1 Cholesterol Synthesis and
  Metabolism
  7-2 Gastrointestinal Absorption of Cholesterol
  and Triglycerides
  7-3 Regulation of Low-Density Lipoprotein
  Receptor and Cholesterol Content
  7-4 High-Density Lipoprotein Metabolism and
  Reverse Cholesterol Transport
  7-5 Hypercholesterolemia
  7-6 Hypercholesterolemic Xanthomatosis
  7-7 Hypercholesterolemic Xanthomatosis
  (cont'd)
  7-8 Abetalipoproteinemia and Tangier
  Disease
  7-9 Hypertriglyceridemia
  7-10 Clinical Manifestations of
  Hypertriglyceridemia
  7-11 Clinical Manifestations of
  Hypertriglyceridemia (cont'd)
  7-12 Atherosclerosis
  7-13 Atherosclerosis(cont'd)
  7-14 Atherosclerosis Risk Factors
  7-15 Metabolic Syndrome
  7-16 Mechanisgg of Action of Lipid-Lowering
  Agents
  7-17 Treatment of Hyperlipidemia
  7-18 Absorption of Essential Vitamins
  7-19 Vitamin B:Deficiency:Beriberi
  7-20 Vitamin B3 Deficiency:Pellagra
  7-21 Vitamin C Deficiency:Scurvy
  7-22 Vitamin A Deficiency
  7-23Celiac Disease and Malabsorption
  7-24 Lysosomal Storage Disorders:
  Sphingolipidoses
  7-25 Anorexia Nervosa
  7-26 Obesity
  7-27 Surgical Treatment Options for
  Obesity
SECTION 8
  GENETICS AND ENDOCRINE
  NEOPLASIA
  8-1 Multiple Endocrine Neoplasia
  Type 1
  8-2 Multiple Endocrine Neoplasia
  Type 2
  8-3Multiple Endocrine Neoplasia
  Type 2(cont'd)
  8-4Von Hippel-Lindau Syndrome
  8-5 Neurofibromatosis Type 1(von
  Recklinghausen Disease)
  8-6Clinical Manifestations of
  Autoimmune Polyglandular
  Syndrome Type 1
  8-7 Carcinoid Syndrome
GLOSSARY OF ABBREVIATIONS
REFERENCES
INDEX